Cell therapy using immunoregulatory T-cells
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United States of America Patent
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Feb 7, 2002
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Feb 7, 2002
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Abstract
The present invention relates to the fields of biology, genetics and medicine. The invention discloses methods and compositions for treating various diseases using populations or compositions of immunoregulatory T cells. The invention discloses that regulatory T cells may be produced and used to control in vivo various pathological conditions, including diseases associated with abnormal T cell activity. The invention relates to the manufacture of such regulatory T cell compositions as well as to their uses for cell therapy treatment. The invention is particularly suited for controlling graft versus host disease in subjects undergoing transplantation (e.g., bone marrow transplantation).
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