Treatment for ischemic stroke
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United States of America Patent
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Issued Date -
Jul 31, 2003
app pub date -
Dec 3, 2002
filing date -
Dec 3, 2001
priority date (Note) -
Abandoned
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Abstract
The present invention relates to a combination of [7-(1H-imidazol-1-yl)-6--nitro-2,3-dioxo-3,4-dihydroquinoxalin-1 (2H)-yl]acetic acid or a salt or hydrate thereof or, preferably, zonampanel together with a tissue plasminogen activator for the therapy of ischemic stroke or for the improvement of neurological symptom accompanied by cerebral infarction, to a method of administration thereof and to a method of therapy therefor. The combination of the present invention showed better effect of reducing the infarct volume than administration of a single component. Therefore, the combination of the present invention is useful as a therapy for ischemic stroke.
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