Vector for analayzing replication mechanism of rna virus and use thereof

Number of patents in Portfolio can not be more than 2000

United States of America Patent

APP PUB NO 20030143528A1
SERIAL NO

10276513

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Abstract

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The object of the present invention is to reproduce conditions where viral proteins can function along with the original life cycle of the viruses and to establish an expression system which can evaluate the function of viral proteins by a reporter gene without generating infectious viruses. The present invention provides an assay system comprising a vector containing DNA coding for RNA virus-derived RNA-dependent RNA polymerase and a vector containing a reporter gene expressed in the anti-sense direction.

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Patent Owner(s)

Patent OwnerAddress
CHUGAI SEIYAKU KABUSHIKI KAISHATOKYO 115
TOKYO METROPOLITAN ORGANIZATION FOR MEDICAL RESEARCHTOKYO

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Katsume, Asao Shizuoka, JP 4 197
Kohara, Michinori Tokyo, JP 37 46
Matsuzaki, Junichi Shizuoka, JP 14 76
Okamoto, Kouichi Shizuoka, JP 28 215

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