Use of a leptospire protein preventing and/or diagnosing and/or treating animal or human leptospirosis
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United States of America Patent
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app pub date -
Aug 7, 2002
filing date -
Feb 8, 2000
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Abstract
The invention concerns the identification of a leptospire protein, polypeptides and antibodies, and their uses for prevention, diagnosis, therapy or experimentation. The invention concerns in particular the isolation, cloning and characterisation of a protein or fragments thereof, containing immunogenic epitopes against leptospiral serovar, in particular pathogenic liptospires. Said protein, polypeptides or peptides derived therefrom, and the corresponding antibodies are particularly useful for preventing, screening or detecting the presence of leptospires in biological samples, for diagnosing leptospirosis, or for treating said pathologies, in human and animal subjects.
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