Inhibitors of rotamase enzyme activity
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United States of America Patent
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Issued Date -
Jun 19, 2003
app pub date -
Aug 27, 2002
filing date -
Jun 7, 1995
priority date (Note) -
Abandoned
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Abstract
This invention relates to the method of using neurotrophic pipecolic acid derivative compounds having an affinity for FKBP-type immunophilins as inhibitors of the enzyme activity associated with immunophilin proteins, and particularly inhibitors of peptidyl-prolyl isomerase or rotamase enzyme activity to stimulate or promote neuronal growth or regeneration.
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