Aggrecanase molecules

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United States of America Patent

APP PUB NO 20030105313A1
SERIAL NO

10057487

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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Novel aggrecanase proteins and the nucleotides sequences encoding them as well as processes for producing them are disclosed. Methods for developing inhibitors of the aggrecanase enzymes and antibodies to the enzymes for treatment of conditions characterized by the degradation of aggrecan are also disclosed.

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Patent Owner(s)

Patent OwnerAddress
GENETICS INSTITUTE LLC87 CAMBRIDGE PARK DRIVE CAMBRIDGE MASSACHUSETTS 02140 UNITED STATES OF AMERICA

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Agostino, Michael J Andover, MA 33 93
Morris, Elisabeth A Sherborn, MA 7 39
Racie, Lisa A Acton, MA 43 127
Twine, Natalie C Goffstown, NH 14 207
Wolfman, Neil Dover, MA 6 60

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