Prion capture

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United States of America Patent

APP PUB NO 20030104480A1
SERIAL NO

10233788

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The claims relate to methods and assays for capturing or detecting prions in a sample using prion-binding materials as well as methods of separating prions from a sample. A method selects a prion-binding material in the form of fibrin(ogen), fibrin(ogen)-related material, fibrin(ogen)-derived material, or mixtures thereof, and contacts a sample with the prion-binding material, such that prions contained in the sample are bound to or associated with the prion-binding material. In another aspect, an assay for detecting the presence of prions obtains prion-binding material in the form of fibrin(ogen), a fibrin(ogen)-related material, a fibrin(ogen)-derived material, or mixtures thereof, contacts the prion-binding material with the sample which may contain prions such that prions contained in the sample are bount to or associated with the prion-binding material, and tests for the presence of prions associated with or bound to the prion-binding material.

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Patent Owner(s)

Patent OwnerAddress
GRADIPORE LIMITEDFRENCHS FOREST NEW SOUTH WALES 2086

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Nair, Chenicheri Hariharan Old Greenwich, CT 17 176
Obradovic, Mina Mosman, AU 1 2
Wang, Kailing Carlingford, AU 6 16

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