Serine protease inhibitor and processes for the preparation thereof
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United States of America Patent
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Issued Date -
May 29, 2003
app pub date -
Aug 27, 2002
filing date -
Aug 27, 2001
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Abstract
A composition comprising a protein having an inhibitory activity for a serine protease and, in particular, for a serine elastase, the protein having a molecular weight of about 46 kDa in a deglycosylated form, and having a molecular weight of about 54 kDa when isolated in a glycosylated form is provided. Methods of using the protein in treatments of diseases where inhibition of a serine protease and, in particular, of a serine elastase is effective are provided as well as compositions, reagents, and kits related thereto.
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