2-Phenyl-quinoline derivatives, preparation method and therapeutic use thereof
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United States of America Patent
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Issued Date -
May 22, 2003
app pub date -
Jun 14, 2002
filing date -
Dec 17, 1999
priority date (Note) -
Abandoned
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Abstract
Compounds of general formula (I) 1 in which: A represents a hydrogen atom or a hydroxyl, B represents a hydrogen atom or a C.sub.1-3 alkyl group, R.sub.1 represents a phenyl optionally substituted with a halogen, a hydroxyl, a C.sub.1-3 alkoxy, C.sub.1-3 alkyl, C.sub.1-3 fluoroalkyl or C.sub.1-2 perfluoroalkyl group, R.sub.2, R.sub.3 and R.sub.6, which may be identical or different, each represent a hydrogen atom, a halogen, a C.sub.1-6 alkyl or C.sub.2-6 alkenyl group, R.sub.4 and R.sub.5, which may be identical or different, each represent a hydrogen atom, a C.sub.1-6 alkyl, C.sub.2-6 alkenyl or C.sub.3-6 cycloalkyl group, or R.sub.4 and R.sub.5 together form a C.sub.2-6 alkylene or C.sub.3-6 alkenylene chain to give, with the nitrogen to which they are attached, a heterocycle, this heterocycle optionally being substituted with a C.sub.1-4 alkyl group. Therapeutic use.
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