Identification of specific modulators of bone formation
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United States of America Patent
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Issued Date -
May 15, 2003
app pub date -
Oct 9, 2002
filing date -
Oct 9, 2001
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Abandoned
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Abstract
The E3 ubiquitin ligases which are specific to ubiquitination of proteins relevant to bone formation are useful targets for protocols or compounds to ameliorate bond disorders. These ligases are .beta.-TrCP, Smurf1 and Smurf2.
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