Multi-analyte assay device with multi-spot detection zone
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United States of America Patent
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Issued Date -
Apr 17, 2003
app pub date -
Sep 16, 2002
filing date -
Sep 17, 2001
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Abandoned
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Abstract
The present invention relates to a solid phase assay device comprising a multi-spot detection zone, and to use thereof in immunochromatographic assays. More precisely, the invention relates to a device for determining analytes in an aqueous sample comprising: an elongate flow matrix (6) allowing lateral transport of fluid therethrough, wherein said matrix comprises a sample application zone (3) and downstream thereof, a detection zone (8) having immobilised capture agents capable of directly or indirectly binding to said analytes, wherein said analytes are detected by allowing a labelled second binding agent to bind directly or indirectly to the analytes. The device is characterised in that the immobilised capture agents are distributed in the detection zone (8) as a plurality of small spots, thereby permitting multi-analyte and/or multi-specificity detection.
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