Elastase inhibitors

Number of patents in Portfolio can not be more than 2000

United States of America Patent

APP PUB NO 20030069187A1
SERIAL NO

09972843

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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Naturally occurring novel elastin derived oligopeptides, having the formula AFP, VPG and AGIP, are disclosed. The oligopeptides are strong competitive inhibitors of elastolytic serine proteases, particularly neutrophil elastases. The novel oligopeptides are useful in methods of inhibiting elastolytic serine protease and methods of detecting a disease characterized by elevated activity of elastolytic serine proteases. Methods for determining the severity of diseases characterized by elevated activity of elastolytic serine proteases are also disclosed.

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Patent Owner(s)

Patent OwnerAddress
NORTH SHORE-LONG ISLAND JEWISH RESEARCH INSTITUTE350 COMMUNITY DRIVE MANHASSET NY 11030

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Faust, Glenn R Roslyn, NY 1 0
Kushner, Leslie Forest Hills, NY 4 36
Mathrubutham, Mahesh Forest Park, IL 5 36
Rao, Srinivasa K New Hyde Park, NY 4 36

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