PRIMER EXTENSION METHODS UTILIZING DONOR AND ACCEPTOR MOLECULES FOR DETECTING NUCLEIC ACIDS

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United States of America Patent

APP PUB NO 20030044780A1
SERIAL NO

09448042

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Abstract

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Methods are provided for selective nucleic acid sequence detection in primer extension reactions of high specificity. These methods are useful for detecting small amounts of mutant nucleic acid in a heterogeneous biological sample. These methods are particularly useful for identifying individuals with gene mutations indicative of early colorectal cancer.

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Patent Owner(s)

Patent OwnerAddress
EXACT SCIENCES CORPORATION5505 ENDEAVOR LANE MADISON WI 53719

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
LAPIDUS, STANLEY N BEDFORD, NH 70 4652
SHUBER, ANTHONY P MILFORD, MA 154 5026

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