Compositions and methods for the rescue of white matter
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United States of America Patent
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Issued Date -
Feb 6, 2003
app pub date -
Dec 7, 2001
filing date -
Dec 8, 2000
priority date (Note) -
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Abstract
Methods and compositions for the protection of white matter of the central nervous system. Specifically, the use of IGF-I, its analogs and mimetics, and the use of IGF-I, its analogs and mimetics in combination with interferons including beta 1 and consensus interferons, to stimulate glial cells such as mature astrocytes to promote remyelination to treat neuronal disease and injury, such as result from, for example, hypoxia, ischemia, trauma, degenerative and demyelinating diseases.
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