Anti-platelet binding proteins and polymer conjugates containing the same
Number of patents in Portfolio can not be more than 2000
United States of America Patent
Stats
-
N/A
Issued Date -
Feb 6, 2003
app pub date -
Feb 27, 2001
filing date -
Feb 29, 2000
priority date (Note) -
Abandoned
status (Latency Note)
Importance
Abstract
The invention provides for anti-platelet binding proteins, and corresponding nucleic acids encoding the binding proteins, that are isolated, for example, from a phage display library by an in vitro selection process. The in vitro selection process involves screening a diverse human antibody variable domain expression library against at least one human platelet antigen to identify clones expressing single-chain antigen-binding proteins useful for inhibiting platelet aggegation and thrombosis, both in vitro and in vivo, as well as in both in vitro and in vivo assays and diagnostic procedures. Anti-platelet binding proteins conjugated to substantially non-antigenic polymers are also provided.
First Claim
Family
International Classification(s)
- C07H:SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTI....
- C12Q:MEASURING OR TESTING PROCESSES INVOLVING ENZYMES O....
- C12P:FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESI....
- C12N:MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF
- G01N:INVESTIGATING OR ANALYSING MATERIALS BY DETERMININ....
- C07K:PEPTIDES
- [Classification Symbol]
- [Patents Count]
Cited Art Landscape
Patent Citation Ranking
Recipient Email Address
Recipient Email Address
Comment
Recipient Email Address
Add to Portfolio(s)
To add this patent to one, or more, of your portfolios, simply click the add button.
This Patent is in these Portfolios:
Add to additional portfolios:
Last Refreshed On:
Changes done successfully