Method for inhibiting apoptosis under ischemic condition
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United States of America Patent
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Issued Date -
Jan 30, 2003
app pub date -
Jul 12, 2002
filing date -
Jan 12, 2000
priority date (Note) -
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Abstract
The present invention relates to a method for inhibiting apoptosis under ischemic condition, which comprises a step of administering antibiotics of quinolones, quinones, aminoglycosides or chloramphenicol to an individual under ischemic condition which lacks an adequate supply of oxygen and glucose. In accordance with the present invention, the antibiotics increase cell viability under hypoxic and hypoglycemic condition, assuring that they can be applied as a therapeutic agent for ischemia-associated diseases such as myocardial infarction and cerebral infarction.
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