Bovine cells expressing adenovirus essential functions for propagation of recombinant adenoviral vectors
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United States of America Patent
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Issued Date -
Jan 9, 2003
app pub date -
Aug 13, 2002
filing date -
Nov 2, 1998
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Abandoned
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Abstract
The invention provides cell lines capable of supporting the replication of a defective recombinant virus vector. In one aspect, bovine cell lines expressing adenovirus E1 functions are provided. The cell lines are useful for the propagation of adenovirus vectors with mutations and/or deletions in E1 and other essential regions of the adenovirus genome.
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