Sample evaporative control
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United States of America Patent
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N/A
Issued Date -
Dec 5, 2002
app pub date -
Nov 2, 2001
filing date -
May 11, 1999
priority date (Note) -
Abandoned
status (Latency Note)
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Abstract
Devices and methods are provided using microfluidic devices for manipulating small volumes and determining a variety of chemical and physical events. The devices rely upon an opening to the atmosphere of a small volume in a zone, where a sample is placed in the zone where evaporation can occur. The zone is maintained in contact with a liquid medium that serves to replenish the liquid in the zone and maintain the composition of the mixture in the zone substantially constant. The diffusion of components in the zone is restricted during the course of the determination by the liquid flux into the zone.
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