Brain-associated inhibitor of tissue-type plasminogen activator
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United States of America Patent
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Issued Date -
Nov 7, 2002
app pub date -
Nov 13, 2001
filing date -
Oct 11, 1996
priority date (Note) -
Abandoned
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Abstract
The present invention relates to a novel BAIT protein which is a member of serpin superfamily which is expressed primarily in brain tissue. In particular, isolated nucleic acid molecules are provided encoding the human and recombinant methods for producing the same. The invention further relates to screening methods for identifying agonists and antagonists of BAIT activity. Also provided are diagnostic methods for detecting nervous system-related disorders and therapeutic methods for treating nervous system-related disorders. Additionally, the present invention is related to methods of treating patients with BAIT polynucleotides or polypeptides, wherein said patients have had seizures or epilepsy.
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