Injectable pharmaceutical composition comprising microdroplets of a camptothecin
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United States of America Patent
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N/A
Issued Date -
Oct 17, 2002
app pub date -
Feb 12, 2001
filing date -
Feb 12, 2001
priority date (Note) -
Abandoned
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Abstract
An injectable pharmaceutical composition comprising: an aqueous suspension of microdroplets suitable for intravenous delivery, the microdroplets having a mean diameter between 200 Angstroms and one micron, the microdroplets comprising a substantially water-insoluble, pharmacologically acceptable liquid, a camptothecin dissolved in the water-insoluble, pharmacologically acceptable liquid, and an outer layer comprising a phospholipid. The pharmaceutical composition is particularly well suited for delivering camptothecins, particularly 9-nitro-camptothecin intravenously.
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