Neutral and anionic colloidal particles for gene delivery

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United States of America Patent

APP PUB NO 20020146829A1
SERIAL NO

09996838

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Abstract

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Processes for making neutral or anionic complexes containing sequestered DNA for gene transfer, by forming a stable colloid containing an aqueous phase having suspended therein a first DNA complex with a cationic surface potential comprising a DNA sequence complexed with a cationic lipid or polymer, and modifying the surface potential of the first DNA complex to form a stable colloid comprising a second DNA complex with a neutral or net anionic surface potential.

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Patent OwnerAddress
CENTELION72-82 RUE LEON GEFFROY VITRY SUR SEINE 94400

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Hofland, Hans Foster City, CA 14 97
Lamons, Donald Emerald Hills, CA 2 30
Meng, Xiao-Ying Freemont, CA 12 197

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