Episomally replicating vector, its preparation and use

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United States of America Patent

SERIAL NO

10059492

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Abstract

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The present invention relates to stably episomally replicating vectors, comprising at least one scaffold/matrix attached region (S/MAR) which binds to nuclear matrix proteins that contain a SAF-A consensus sequence, at least one viral or eukaryotic origin of replication (ORI), at least one transcription unit transcribed in direction towards the S/MAR, and a polyadonylation signal within the S/MAR or in transriptional direction after the S/MAR, cells comprising these, processes for their preparation, and their use, in particular as a medicament or diagnostic.

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Patent Owner(s)

Patent OwnerAddress
MULTIGENE BIOTECH GMBHAM HUBLAND BIOZENTRUM 97074 WURZBURG

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Baiker, Armin Lauffen/Neckar, DE 2 18
Bode, Jurgen Schoppenstedt, DE 6 80
Fetzer, Christian Munchen, DE 2 18
Lipps, Hans-Joachim Tubingen, DE 2 18
Piechaczek, Christoph Munster, DE 2 18

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