Method for purifying a biological composition
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United States of America Patent
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app pub date -
Sep 4, 2001
filing date -
Jan 22, 2001
priority date (Note) -
Abandoned
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Abstract
Disclosed is a method for reducing the amount of extracellular fluid in a blood cell suspension. The method includes providing a large volume of a blood cell suspension that includes blood cells and extracellular fluid. The blood cell suspension is washed with a wash solution under conditions sufficient to lower the concentration of the extracellular fluid in the blood cell composition at least 10.sup.3-fold relative to the amount of extracellular fluid in the blood cell suspension. The method can also be used to lower the concentration of analytes (such as prions) in the blood cell suspension. Also provided is a blood cell suspension produced by the washing method.
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