COMBINATORIAL ACTIVE COMPOUND SYNTHESIS AND ITS INTERMEDIATES
Number of patents in Portfolio can not be more than 2000
United States of America Patent
Stats
-
N/A
Issued Date -
Sep 12, 2002
app pub date -
Oct 10, 1997
filing date -
Oct 15, 1996
priority date (Note) -
Abandoned
status (Latency Note)
Importance
Abstract
The invention relates to a resin-bound synthesis process for the preparation of chemical compounds of the formula (I) R.sup.1--SO.sub.2--NH--CO--R.sup.2 (I) in which R.sup.1 and R.sup.2 each are an organic radical, which comprises a) reacting a resin-linker compound of the formula [resin polymer]-[L-Nuc].sub.n (II) in which nucleofugic groups Nuc are bonded to a resin [=resin polymer] via the linker L, with an acylsulfonamide of the formula E.sup.1--SO.sub.2--NH--CO--E.sup.2 (III) in which E.sup.1 and E.sup.2 independently of one another in each case are an organic radical suitable for the preparation of the radicals R.sup.1 and R.sup.2 in compound (I), in the presence of a condensing agent to give a resin-bound adduct of the formula (IV) 1 in which [resin polymer], L, n, E.sup.1 and E.sup.2 are as defined in formula (II) or formula (III), b) derivatizing the adduct (IV) obtained in one or more further reaction steps on the organic radicals E.sup.1 or E.sup.2 to give the radicals R.sup.1 or R.sup.2, and c) cleaving the compound of the formula (I) from the resin-linker adduct of the formula (IV') obtained.
First Claim
Family
International Classification(s)
- [Classification Symbol]
- [Patents Count]
Cited Art Landscape
Patent Citation Ranking
Recipient Email Address
Recipient Email Address
Comment
Recipient Email Address
Add to Portfolio(s)
To add this patent to one, or more, of your portfolios, simply click the add button.
This Patent is in these Portfolios:
Add to additional portfolios:
Last Refreshed On:
Changes done successfully