Inhibitors of alternative alleles of genes encoding products that mediate cell response to environmental changes
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United States of America Patent
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app pub date -
Feb 14, 2001
filing date -
Mar 19, 1998
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Abstract
Disclosed are methods for the treatment of proliferative disorders using compounds and/or environmental conditions which result in a difference in sensitivity of targeted and non-targeted cells. Certain of the methods involve the identification and use of allele-specific inhibitors of conditionally essential genes.
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