Powder compositions
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United States of America Patent
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Issued Date -
Aug 29, 2002
app pub date -
Jun 8, 2001
filing date -
Jun 8, 2000
priority date (Note) -
Abandoned
status (Latency Note)
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Abstract
A gel-forming free-flowing powder suitable for use as a vaccine is prepared by spray-drying or spray freeze-drying an aqueous suspension that contains an antigen adsorbed to an aluminum salt or calcium salt adjuvant, a saccharide, an amino acid or a salt thereof, and a colloidal substance. Powder for vaccine purposes are also prepared by spray freeze-drying an aqueous suspension of such an adjuvant having an antigen adsorbed therein. Processes for forming these powder compositions are also described, as well as methods of using the compositions in a vaccination procedure.
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