Use of dendroaspin as a scaffold for non-dendroaspin domains
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United States of America Patent
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Issued Date -
Aug 29, 2002
app pub date -
Feb 5, 2001
filing date -
Feb 5, 2000
priority date (Note) -
Abandoned
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Abstract
The use of dendroaspin as a scaffold for one or more non-wild-type dendroaspin domains, the dendroaspin scaffold being modified in that the native RGD motif has been deleted or has been replaced by (i) an amino acid sequence having no integrin-binding activity or (ii) an integrin-binding amino acid sequence other than RGD which contains aspartic acid (D) or glutamic acid (E).
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