Methods for stabilization and renaturation of proteins using nucleolar protein B23
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United States of America Patent
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Issued Date -
Aug 22, 2002
app pub date -
Mar 18, 2002
filing date -
Mar 30, 1999
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The present invention provides methods for stabilizing proteins, preventing protein aggregation, renaturation of previously-denatured proteins, reactivating a protein that has been inactivated by denaturation, preserving enzyme activities under conditions of elevated temperatures, inducing thermotolerance in bacteria, increasing the temperature optimum for the activity of an enzyme, and preventing formation of inclusion bodies by bacterially-expressed recombinant proteins.
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