CDR-GRAFTED ANTIBODIES
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United States of America Patent
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app pub date -
Jan 13, 1999
filing date -
Dec 21, 1989
priority date (Note) -
Abandoned
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Abstract
There are disclosed: a CDR-grafted antibody having at least one chain wherein the framework regions are predominantly derived from a first antibody (acceptor) and at least one CDR is derived from a second antibody (donor), the CDR-grafted antibody being capable of binding to the CD4 antigen; processes for its production; nucleotide sequences for use in its production; compositions containing
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