Immunotherapeutic stress protein-peptide complexes against cancer
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United States of America Patent
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Issued Date -
May 23, 2002
app pub date -
Nov 14, 2001
filing date -
Sep 30, 1994
priority date (Note) -
Abandoned
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Abstract
Disclosed is a method for inhibiting the proliferation of a tumor in a mammal. The method involves the steps of (a) isolating a stress protein-peptide complex from tumor cells previously removed from the mammal and (b) administering the isolated stress protein-peptide complex back to the mammal in order to stimulate in the mammal an immune response against the tumor from which the complex was isolated. Stress protein-peptide complexes having particular utility in the practice of the instant invention include the Hsp70-peptide, Hsp90-peptide and gp96-peptide complexes.
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