EXPRESSION OF SURFACE LAYER PROTEINS
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United States of America Patent
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Issued Date -
Apr 25, 2002
app pub date -
Aug 21, 1998
filing date -
Jan 14, 1994
priority date (Note) -
Abandoned
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Abstract
A host cell which is provided with a S-layer comprising a fusion polypeptide consisting essentially of: (a) at least sufficient of a S-layer protein for a S-layer composed thereof to assemble, and (b) a heterologous polypeptide which is fused to either the carboxy terminus of (a) or the amino terminus of (a) and which is thereby presented on the outer surface of the said cell; can be used as a vaccine, for screening for proteins and antigens and as a support for immobilizing an enzyme, peptide or antigen.
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