4-aza-steroids
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United States of America Patent
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N/A
Issued Date -
Mar 21, 2002
app pub date -
Jul 23, 2001
filing date -
May 7, 1997
priority date (Note) -
Abandoned
status (Latency Note)
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Abstract
4-Aza-steroid compounds are provided, which have functional groups at one or more of positions 7, 11 and 15, such as hydroxyl or hydroxyl derivative groups. The compounds are active against 5-.alpha.-reductase giving indications of utility in combating prostate cancer. The compounds can be prepared by chemo-enzymatic synthesis from easily available 4-aza-steroids.
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