CYCLOPHOSPHAMIDE FILM-COATED TABLETS
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United States of America Patent
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N/A
Issued Date -
Nov 29, 2001
app pub date -
Jun 15, 1999
filing date -
Jun 15, 1998
priority date (Note) -
Abandoned
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Abstract
1. [sic] The invention relates to film-coated tablets with cyclophosphamide as active compound, which in the core comprise cyclophosphamide, one or more fillers, one or more dry binders but no preswollen starch, flow regulators and lubricants. According to a preferred embodiment of the invention, the core of the film-coated tablet comprises as a filler lactose monohydrate, D-mannitol or CaHPO.sub.4, nonpreswollen cornstarch or microfine cellulose as a dry binder, highly disperse silica as a flow regulator and magnesium stearate, stearic acid, glycerol palmitostearate, polyethylene glycol, talc or glycerol monobeherate [sic] as a lubricant.
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