Asymmetric synthesis of quinazolin-2-ones useful as HIV reverse transcriptase inhibitors
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United States of America Patent
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Issued Date -
Nov 22, 2001
app pub date -
Mar 22, 2001
filing date -
Mar 23, 2000
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Abandoned
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Abstract
This invention relates generally to the asymmetric synthesis of quinazolin-2-ones that are useful as inhibitors of HIV reverse transcriptase. The synthesis is accomplished through the chiral ligand mediated addition of cyclopropylacetylide.
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