Novel resin materials and their use for recovering proteins or peptides
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United States of America Patent
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Issued Date -
Nov 8, 2001
app pub date -
Feb 8, 2001
filing date -
Feb 8, 2000
priority date (Note) -
Abandoned
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Abstract
Processes for recovering a target protein having milk clotting activity including chymosin, and other target proteins or peptides from an aqueous medium containing such a protein using a resin material comprising a solid support matrix and, covalently bound to the matrix, a target protein binding ligand selected from benzylamine or a derivative thereof; an alkylamine, an alkenylamine, an alkynylamine, an alkoxyamine and an amine of mono- or bicyclic aromatic or heteroaromatic moieties, any of which is optionally substituted with at least one group other than an acidic group. The resin material may conveniently be in a packed or a fluidised or expanded bed.
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