Microorganisms and methods for enhancing the availability of reducing equivalents in the presence of methanol, and for producing 1,4-butanediol related thereto

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United States of America

PATENT NO 12264354
APP PUB NO 20180030484A1
SERIAL NO

15488320

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Abstract

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Provided herein is a non-naturally occurring microbial organism having a methanol metabolic pathway that can enhance the availability of reducing equivalents in the presence of methanol. Such reducing equivalents can be used to increase the product yield of organic compounds produced by the microbial organism, such as 1,4-butanediol (BDO). Also provided herein are methods for using such an organism to produce BDO.

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GENOMATICA INCSAN DIEGO CA 92121

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  • 2017 Application Filing Year
  • C12P Class
  • 1642 Applications Filed
  • 1019 Patents Issued To-Date
  • 62.06 % Issued To-Date
Click to zoom InYear of Issuance% of Matters IssuedCumulative IssuancesYearly Issuances2017201820192020202120222023202420250255075100

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Andrae, Stefan San Diego, US 33 120
Burgard, Anthony P Bellefonte, US 199 3095
Osterhout, Robin E San Diego, US 156 1473
Pharkya, Priti San Diego, US 156 1697
Tracewell, Cara Ann Solana Beach, US 33 51
Van, Dien Stephen J Encinitas, US 54 787

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