Evaporation management in digital microfluidic devices

Number of patents in Portfolio can not be more than 2000

United States of America

PATENT NO 12263483
APP PUB NO 20240198341A1
SERIAL NO

18416693

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Abstract

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Described herein are digital microfluidic (DMF) devices and corresponding methods for managing reagent solution evaporation during a reaction. Reactions on the DMF devices described here are performed in an air or gas matrix. The DMF devices include a means for performing reactions at different temperatures. To address the issue of evaporation of the reaction droplet especially when the reaction is performed at higher temperatures, a means for introducing a replenishing droplet has been incorporated into the DMF device. A replenishing droplet is introduced every time when it has been determined that the reaction droplet has fallen below a threshold volume. Detection and monitoring of the reaction droplet may be through visual, optical, fluorescence, colorimetric, and/or electrical means.

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Patent Owner(s)

Patent OwnerAddress
MIROCULUS INC458 BRANNAN STREET SAN FRANCISCO CA 94107

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Branda, Steven Livermore, US 8 91
Jebrail, Mais J Toronto, CA 23 462
Renzi, Ronald Francis Tracy, US 4 42

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