Mixed mode cation exchange chromatography ligands based on 1,3-dioxoisoindolin-2-yl structures

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United States of America

PATENT NO 12263467
APP PUB NO 20240001338A1
SERIAL NO

18360870

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Abstract

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The subject invention pertains to proteins are purified by a mixed-mode chromatography system formed by attaching a ligand with cation exchange and hydrophobic 1,3-dioxoisoindolin-2-yl group functionalities to a large-pore support matrix, the only linkage between the ligand and the support matrix being a chain having a backbone of one, two, three, four, or five atoms between the hydrophobic group and the support matrix.

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Patent Owner(s)

  • BIO-RAD LABORATORIES INC.

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Belisle, Christopher Walnut Creek, US 26 26
Liao, Jiali San Ramon, US 20 46
Lozano, Edwin Berkeley, US 3 0

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