Human alpha-galactosidase variants

Number of patents in Portfolio can not be more than 2000

United States of America

PATENT NO 12263207
APP PUB NO 20210244804A1
SERIAL NO

17196858

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Abstract

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The present invention provides engineered human alpha-galactosidase polypeptides and compositions thereof. The engineered human alpha-galactosidase polypeptides have been optimized to provide improved stability under both acidic (pH<4.5) and basic (pH>7) conditions. The invention also relates to the use of the compositions comprising the engineered human alpha-galactosidase polypeptides for therapeutic purposes.

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Patent Owner(s)

Patent OwnerAddress
CROSSWALK THERAPEUTICS INC790 MEMORIAL DRIVE SUITE 302 CAMBRIDGE MA 02319

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Agard, Nicholas J San Francisco, US 62 532
Huisman, Gjalt W Redwood City, US 150 2275
Miller, Mathew G San Carlos, US 24 52
Zhang, Xiyun Fremont, US 141 584

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