Photonic structures and integrated device for detecting and analyzing molecules

Number of patents in Portfolio can not be more than 2000

United States of America

PATENT NO 12259324
APP PUB NO 20230375475A1
SERIAL NO

18356150

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Abstract

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System and methods for analyzing single molecules and performing nucleic acid sequencing. An integrated device may include multiple pixels with sample wells configured to receive a sample, which when excited, emits radiation. The integrated device includes a surface having a trench region recessed from a portion of the surface and an array of sample wells, disposed in the trench region. The integrated device also includes a waveguide configured to couple excitation energy to at least one sample well in the array and positioned at a first distance from a surface of the trench region and at a second distance from the surface in a region separate from the trench region. The first distance is smaller than the second distance. The system also includes an instrument that interfaces with the integrated device. The instrument may include an excitation energy source for providing excitation energy to the integrated device by coupling to an excitation energy coupling region of the integrated device.

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Patent Owner(s)

Patent OwnerAddress
QUANTUM-SI INCORPORATED530 OLD WHITFIELD STREET GUILFORD CT 06437

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Beach, James Austin, US 32 191
Cipriany, Benjamin Branford, US 44 889
Fife, Keith G Palo Alto, US 221 4923
Ghasemi, Farshid Guilford, US 32 599
Glenn, Paul E Wellesley, US 53 843
Kabiri, Ali Guilford, US 59 845
Lackey, Jeremy Foster City, US 76 1160
Preston, Kyle Guilford, US 39 256
Rothberg, Jonathan M Miami Beach, US 567 39206
Schmid, Gerard Guilford, US 99 1172
Sickler, Jason W Arlington, US 47 1084
West, Lawrence C San Jose, US 95 1989

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