Humanized cell line

Number of patents in Portfolio can not be more than 2000

United States of America

PATENT NO 12258557
APP PUB NO 20240318167A1
SERIAL NO

18525460

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Abstract

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A mammalian or avian cell line that expresses high levels of human influenza virus receptors is provided. In one embodiment, the cell line supports human influenza virus, e.g., human A/H3 influenza virus, isolation and growth much more effectively than corresponding conventional (unmodified) cells or in corresponding human virus receptor-overexpressing cells, and the propagated viruses may maintain higher genetic stability than in the corresponding cells.

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Patent Owner(s)

  • WISCONSIN ALUMNI RESEARCH FOUNDATION (WARF); THE UNIVERSITY OF TOKYO

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Imai, Masaki Kawasaki, JP 9 19
Kawaoka, Yoshihiro Middleton, US 101 1962
Takada, Kosuke Tokyo, JP 30 66

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