Methods for dynamic evolution and monitoring of characteristics in living cells using a microfluidic-enabled multi-well cell culture devices and systems
Number of patents in Portfolio can not be more than 2000
United States of America
Stats
-
Mar 25, 2025
Grant Date -
Dec 30, 2021
app pub date -
Nov 14, 2019
filing date -
Nov 14, 2019
priority date (Note) -
In Force
status (Latency Note)
Importance
Abstract
A method for dynamic evolution and/or adaptation and monitoring of characteristics in living cells is provided, wherein the method may be performed at a microfluidic-enabled cell-culture device comprising pneumatic layer for directing flow of fluid to a plurality of individually addressable wells, and one or more sensors configured to detect data regarding environments inside one or more of the plurality of wells. The method may involve culturing a population of cells in a first well of the plurality of wells, perturbing one or more characteristics of an environment in the first well following the culturing of the population of cells, monitoring one or more characteristics of the population of cells in the first well, and removing all or part of the evolved/adapted population of cells from the first well.
First Claim
Other Claims data not available
Family
International Classification(s)
- 2019 Application Filing Year
- C12N Class
- 8554 Applications Filed
- 3796 Patents Issued To-Date
- 44.38 % Issued To-Date
Cited Art Landscape
Patent Citation Ranking
- 0 Citation Count
- C12N Class
- 0 % this patent is cited more than
- < 1 Age
Maintenance Fees
| Fee | Large entity fee | small entity fee | micro entity fee | due date |
|---|---|---|---|---|
| 3.5 Year Payment | $1600.00 | $800.00 | $400.00 | Sep 25, 2028 |
| 7.5 Year Payment | $3600.00 | $1800.00 | $900.00 | Sep 25, 2032 |
| 11.5 Year Payment | $7400.00 | $3700.00 | $1850.00 | Sep 25, 2036 |