Bispecific constructs for target and complement engagement

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United States of America

PATENT NO 12258416
SERIAL NO

18618626

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Abstract

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Single domain antibodies are provided, which are capable of specifically binding to an epitope of a human complement factor selected from the group consisting of C1q, C3, C4 and/or the proteolytic derivatives C3b and C4b. Further the use of the antibodies are provided for methods in modulating the activity of the complement system as well as methods of treating disorders associated with complement activation.

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AARHUS UNIVERSITETNORDRE RINGGADE 1 AARHUS C 8000

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Andersen, Gregers Rom Brabrand, DK 3 0
Jensen, Rasmus Kjeldsen Aarhus C, DK 3 0
Laursen, Nick Stub Aarhus C, DK 3 0
Pedersen, Dennis Vestergaard Aarhus C, DK 2 0
Pedersen, Henrik Aarhus C, DK 137 2074
Thiel, Steffen Risskov, DK 25 516
Zarantonello, Alessandra Aarhus C, DK 3 0

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