Stabilized immunoglobulin domains

Number of patents in Portfolio can not be more than 2000

United States of America

PATENT NO 12258371
APP PUB NO 20210054021A1
SERIAL NO

16943067

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ATTORNEY / AGENT: (SPONSORED)

Importance

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Abstract

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The invention relates autonomous VH domains (aVH) with cysteines in positions 52a and 71 or in positions 33 and 52 in order to stabilize the autonomous VH domains. Said cysteines are capable of forming a disulfide bond and/or form a disulfide bond under suitable conditions. The invention further relates to aVH libraries.

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Patent Owner(s)

  • HOFFMAN-LA ROCHE INC.

International Classification(s)

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Deak, Codarri Laura Schlieren, CH 1 2
Dengl, Stefan Penzberg, DE 53 220
Fischer, Jens Penzberg, DE 60 413
Hofer, Thomas Schlieren, CH 62 321
Lariviere, Laurent Penzberg, DE 20 50
Moessner, Ekkehard Schlieren, CH 194 2920
Seeber, Stefan Penzberg, DE 102 1363
Umana, Pablo Schlieren, CH 247 5409
Zagdoun, Anne-Claire Schlieren, CH 1 2

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