Preparation method for three-layer artificial blood vessel and application thereof

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United States of America

PATENT NO 12257141
APP PUB NO 20210338410A1
SERIAL NO

17377427

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Abstract

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The present invention provides a preparation method preparation method for three-layer artificial blood vessel and application thereof. The three-layer artificial blood vessel comprise three layers, electrospinning inner layer, dense middle layer and electrospinning outer layer, the three-layer structure is closely combined and difficult to separate. The inner layer with a cytoskeleton-like structure can promote the formation of intima; the dense middle layer can effectively prevent the leakage of biomacromolecules and increase the puncture resistance of the whole artificial blood vessel; and the outer layer can promote the growth of tissue cells and better integrate with tissue. The three-layer artificial blood vessel provided by the invention has excellent blood compatibility, good flexibility, good puncture resistance and interlayer peeling resistance. The preparation method is convenient and is suitable for industrial scale production.

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Patent Owner(s)

Patent OwnerAddress
WUHAN YOUNGSEN BIOTECH CO LTDBUILDING A04 PHASE 1 ENTERPRISE ACCELERATOR BIOMEDICAL PARK NO 858 GAOXIN AVENUE EAST-LAKE NEW TECHNOLOGY DEVELOPMENT ZONE WUHAN

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Li, Jiarong Wuhan, CN 9 1
Liu, Jianpeng Wuhan, CN 11 4
Liu, Sishi Wuhan, CN 5 0
Ouyang, Chenxi Wuhan, CN 5 0
Wang, Chenhong Wuhan, CN 3 28

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