Nucleic acid molecules encoding binding proteins for gastric inhibitory peptide receptor (GIPR)

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United States of America

PATENT NO 12252540
APP PUB NO 20220025059A1
SERIAL NO

17332578

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Abstract

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Methods of treating metabolic diseases and disorders using an antigen binding protein specific for the GIPR polypeptide are provided. In various embodiments the metabolic disease or disorder is type 2 diabetes, obesity, dyslipidemia, elevated glucose levels, elevated insulin levels and diabetic nephropathy. In certain embodiments the antigen binding protein is administered in combination with a GLP-1 receptor agonist.

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Patent Owner(s)

  • AMGEN INC.

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Agrawal, Neeraj Thousand Oaks, US 39 1209
Bates, Darren L Oak Park, US 11 35
Clavette, Brandon C P Coquitlam, CA 3 22
Foltz, Ian N Burnaby, CA 5 22
Ho, Shu-yin Thousand Oaks, US 6 23
Komorowski, Renee Ventura, US 3 22
Lloyd, David J Thousand Oaks, US 22 199
Min, Xiaoshan Burlingame, US 19 150
Murawsky, Christopher Roberts Creek, CA 10 67
Shi, Donghui Thousand Oaks, US 10 54
Sivits,, Jr Glenn N Newbury Park, US 4 22
Veniant-Ellison, Murielle M Thousand Oaks, US 12 67
Wang, Jinghong Palo Alto, US 16 38
Wang, Zhulun Palo Alto, US 43 413
Yie, Junming Warren, US 12 168

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