Neuroactive steroids and their methods of use

Number of patents in Portfolio can not be more than 2000

United States of America

PATENT NO 12252509
APP PUB NO 20240309042A1
SERIAL NO

18616903

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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Provided herein is a compound of Formula (I) or a pharmaceutically acceptable salt thereof, wherein R19, R5, R3a, R1a, R1b, R2a, R2b, R4a, R4b, R6a, R6b, R7a, R7b, R11a, R11b, R12a, R12b, R18, RD, and q are defined herein. L is selected from the group consisting of: wherein A indicates the point of attachment at C17 and wherein X is selected from the group consisting of —C(O)N(R55a)(R55b), —N(R55a)(R55b), —N(R55b)C(O)(R55a), and R55C wherein R55c is carbon-bound substituted or unsubstituted heteroaryl or substituted or unsubstituted aryl. Also provided herein are pharmaceutical compositions comprising a compound of Formula (I) and methods of using the compounds, e.g., in the treatment of CNS-related disorders.

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Patent Owner(s)

  • SAGE THERAPEUTICS, INC.

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Blanco-Pillado, Maria Jesus Arlington, US 32 102
Morningstar, Marshall Lee Framingham, US 18 25
Salituro, Francesco G Marlborough, US 216 2924

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