Carrier-protein polysaccharide conjugation methods

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United States of America

PATENT NO 12252454
APP PUB NO 20230183147A1
SERIAL NO

18171055

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Abstract

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The present disclosure provides methods of preparing heteroaryl-containing compounds, wherein an azide-alkyne cycloaddition is accelerated in the presence of lauryldimethylamine oxide (LDAO). The present disclosure further provides conjugates of polypeptides and antigens prepared using such methods.

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Patent Owner(s)

  • VAXCYTE, INC.

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Fairman, Jeffery C Mountain View, US 5 8
Kapoor, Neeraj Foster City, US 15 297
Pill, Lucy Estella Burlingame, US 1 0
Snyder, Scott Union City, US 24 383

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