Inactivating bacteria with electric pulses and antibiotics

Number of patents in Portfolio can not be more than 2000

United States of America

PATENT NO 12251439
APP PUB NO 20240066128A1
SERIAL NO

18490238

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Abstract

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Provided is a method of reducing a number of viable microbes, including contacting microbes with an antibiotic compound and applying pulses of electricity having a duration of between about 50 nanoseconds and about 900 nanoseconds. The pulses of electricity may have an intensity between about 20 kV/cm and about 40 kV/cm. The pulses of electricity may be applied at a frequency of between about 0.1 Hz and about 10 Hz. The microbes may be a gram-negative or a gram-positive strain of bacteria and the antibiotic may be applied at a concentration for a duration, wherein applying the antibiotic to the strain at the concentration for the duration does not reduce a viable number of bacteria of the strain as much, or at all, when the pulses of electricity are not also applied.

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Patent Owner(s)

  • PURDUE RESEARCH FOUNDATION; NANOVIS, LLC.

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Detwiler, David Alan Columbia City, US 5 5
Garner, Allen Lawrence West Lafayette, US 21 65
Vadlamani, Ram Anand West Lafayette, US 4 5

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