Method of improved sequencing by strand identification

Number of patents in Portfolio can not be more than 2000

United States of America

PATENT NO 12247252
APP PUB NO 20230167493A1
SERIAL NO

17815815

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Abstract

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In some aspects, the present disclosure provides methods for identifying sequence variants, as well as methods of determining copy number of a genetic locus in a sample. Systems and kits for performing methods of the disclosure, as well as compositions produced by or useful in methods of the disclosure are also provided. In some embodiments, methods comprise extending 3′ ends of polynucleotides by adding one or more pre-determined nucleotides. In some embodiments, methods comprise use of a strand-tagging sequence.

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Patent Owner(s)

  • ACCURAGEN HOLDINGS LIMITED

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Faham, Malek Burlingame, US 97 5030
Lin, Shengrong Fremont, US 32 610
Lu, Yontao Sunnyvale, US 3 11
Sun, Zhaohui Albany, US 48 1204
Tang, Ling Fung San Francisco, US 7 39
Wang, Yingyu Mountain View, US 9 42
Weng, Li Fremont, US 38 1145

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